Title of article
1,3-Diastereocontrol in acyclic radical allylations
Author/Authors
Enholm، نويسنده , , Eric J and Lavieri، نويسنده , , Sophie and Cordَva، نويسنده , , Tanya and Ghiviriga، نويسنده , , Ion، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
531
To page
534
Abstract
The radical allylation of an acyclic α-hydroxyketone with allyltributyltin under chelation-controlled conditions is reported. Several reaction conditions were explored, including radical initiators, solvents, and temperatures to improve the yield and the diastereomeric ratio. Some Lewis acids, like magnesium bromide etherate and zinc chloride, gave superior diastereomeric ratios (up to 100:1) and good yields.
Keywords
allyltributyltin , Free radical , diastereoselective
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1660129
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