Title of article :
Barbier-type allylation of iminium ions generated in situ in aqueous medium
Author/Authors :
Estevam، نويسنده , , Idلlia H.S. and Bieber، نويسنده , , Lothar W.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Abstract :
Iminium ions, generated in aqueous solution from secondary amines and formaldehyde, undergo a Barbier-type allylation mediated by tin, aluminum and zinc. The reaction is catalyzed by copper and produces tertiary homoallylamines in up to 85% yield.
Keywords :
Barbier reaction , allylation , iminium salts , aqueous solvent
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
