Title of article :
2,5-Bis-(butyltelluro) thiophene as a convenient precursor for the synthesis of 2,5-bis-(acetylenic) thiophenes
Author/Authors :
Zeni، نويسنده , , Gilson and Nogueira، نويسنده , , Cristina W. and Silva، نويسنده , , Dagoberto O. and Menezes، نويسنده , , Paulo H. and Braga، نويسنده , , Antonio L. and Stefani، نويسنده , , Hélio A. and Rocha، نويسنده , , Joمo B.T.، نويسنده ,
Abstract :
Both symmetrically and unsymmetrically substituted 2,5-bis-(acetylenic) thiophene derivatives were obtained in good yields under mild conditions through palladium-catalyzed cross coupling reaction of 2,5-bis-(butyltelluro) thiophene 2 and terminal alkynes. The methodology represents a general and efficient protocol for carrying out the synthesis of thiophene derivatives with potential biological activities.
Keywords :
Tellurium , cross-coupling , PALLADIUM , Thiophenes
