Title of article
A general approach toward the synthesis of 8-acylamidopyrazolo[1,5-a]-1,3,5-triazines
Author/Authors
Raboisson، نويسنده , , Pierre and Schultz، نويسنده , , Dominique and Lugnier، نويسنده , , Claire and Mathieu، نويسنده , , Romain and Bourguignon، نويسنده , , Jean-Jacques، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
3
From page
703
To page
705
Abstract
An expedient synthesis of 8-acylamidopyrazolo[1,5-a]-1,3,5-triazines was developed by treating 8-amino-4-[N-(4-aminophenyl)-N-(methyl)amino]pyrazolo[1,5-a]-1,3,5-triazine with various acyl chlorides following by the displacement of the so-formed N-(methyl)-N-[4-(acylamido)phenyl]amino leaving group with various amines. Applications to high-throughput synthesis are suggested.
Keywords
adenine , bioisoster , 5-a]-1 , 3 , 5-triazine , activating group
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1660240
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