Title of article
Enantiodivergent syntheses of γ-substituted butenolides with tertiary and quaternary asymmetric centers
Author/Authors
Suzuki، نويسنده , , Katsufumi and Inomata، نويسنده , , Kohei، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
5
From page
745
To page
749
Abstract
Continuous nucleophilic addition with several organometallic reagents to tricyclic lactone (−)-1 proceeded diastereoselectively. Newly generated tertiary and quaternary asymmetric centers were controlled by the order in which the nucleophilic reagents were added. Using this methodology, enantiodivergent syntheses of several γ-substituted butenolides with tertiary and quaternary asymmetric centers were established from a single chiral material.
Keywords
chiral synthesis , chiral building block , Lactones , nucleophilic addition , butenolides
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1660264
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