Author/Authors :
Corbett، نويسنده , , Matthew S. and Liu، نويسنده , , Xiang and Sanyal، نويسنده , , Amitav and Snyder، نويسنده , , John K.، نويسنده ,
Abstract :
Chiral anthracene template, 10-methyl-9-(1-methoxy-2,2,2-trifluoroethyl)anthracene undergoes highly diastereoselective cycloadditions with maleic anhydride and 5-acetoxy-2(5H)-furanone. Subsequent regioselective and stereoselective manipulations demonstrate the synthetic utility in conversions to enantioenriched butenolides, and elucidate the origin of diastereoselection.
