Author/Authors :
Santagada، نويسنده , , Vincenzo and Fiorino، نويسنده , , Ferdinando and Perissutti، نويسنده , , Elisa and Severino، نويسنده , , Beatrice and Terracciano، نويسنده , , Sara and Teixeira، نويسنده , , Cleber Evandro and Caliendo، نويسنده , , Giuseppe، نويسنده ,
Abstract :
A novel and convenient microwave-assisted synthesis of an active metabolite (EXP-3174) of losartan is described. Room temperature and microwave irradiation of the reactions are compared. Synthesis by microwave irradiation gave the desired compound in higher yields and in shorter reaction times than those obtained at room temperature.