Title of article :
Gymnasterol, a new antitumor steroid against IGF-dependent cells from Gymnascella dankaliensis
Author/Authors :
Hayakawa، نويسنده , , Yoichi and Furihata، نويسنده , , Kazuo and Shin-ya، نويسنده , , Kazuo and Mori، نويسنده , , Toshiya، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Abstract :
A new antitumor substance, gymnasterol (1), was isolated from the culture broth of Gymnascella dankaliensis. The structure of 1 was determined to be a novel ergostane steroid on the basis of NMR studies. Gymnasterol selectively inhibited IGF-1-dependent growth of MCF-7 human breast cancer cells.
Keywords :
gymnasterol , Steroid , antitumor substance , Insulin-Like Growth Factor
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
