Author/Authors :
Hamada، نويسنده , , Toshiyuki and Hirota، نويسنده , , Hiroshi and Yokoyama، نويسنده , , Shigeyuki and Yamaguchi، نويسنده , , Masanori and Otsubo، نويسنده , , Nobumasa and Ishida، نويسنده , , Hideharu and Kiso، نويسنده , , Makoto and Kanamori، نويسنده , , Akiko and Kannagi، نويسنده , , Reiji، نويسنده ,
Abstract :
The structure of cyclic sialyl 6-sulfo Lewis x, a new biologically dormant form of L-selectin ligand, was determined unambiguously by the accurate NMR analysis to have the lactamized 5,2B conformation of its sialic acid. For the NMR structure elucidation were used various informations, such as chemical shifts values, appearance of amide proton, and NOE.
Keywords :
cyclic sialyl 6-sulfo Lewis x , L-selectin , NMR , 5 , Structure elucidation , 2B boat conformation
