Title of article
Solvent-free catalytic preparation of 1,1-diacetates from aldehydes using a Wells–Dawson acid (H6P2W18O62·24H2O)
Author/Authors
Romanelli، نويسنده , , Gustavo P. and Thomas، نويسنده , , Horacio J. and Baronetti، نويسنده , , Graciela T. and Autino، نويسنده , , Juan C.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
3
From page
1301
To page
1303
Abstract
Aromatic and aliphatic aldehydes are transformed in 1,1-diacetates (acylals) in mild conditions, by a treatment with acetic anhydride and a Wells–Dawson acid (H6P2W18O62·24H2O). gem-Diacetylation proceeds in Ac2O with a little as 1% mol Wells–Dawson acid at room temperature and under solventless conditions, obtaining very good to excellent yields (88–98%) of 1,1-diacetates (19 examples). Neither 4-dimethylaminobenzaldehyde nor ketones react under the same conditions.
Keywords
Protecting group , aldehyde , 1 , 1-Diacetate , Acylal , Heteropolyacid , Wells–Dawson catalyst
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1660569
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