Title of article
An efficient synthesis of 6-hydroxymelatonin, a human metabolite of melatonin
Author/Authors
Karam، نويسنده , , Omar and Zunino، نويسنده , , Fabien and Chagnaut، نويسنده , , Vincent and Jouannetaud، نويسنده , , Marie-Paule and Jacquesy، نويسنده , , Jean Claude، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
3
From page
1511
To page
1513
Abstract
A four-step synthesis of 6-hydroxymelatonin 5, major human metabolite of melatonin 1, is reported starting from melatonin. The synthesis involves in the keys steps a regioselective Friedel–Crafts acylation followed by a Baeyer–Villiger oxidation. The overall yield is 48%.
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1660694
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