Title of article :
Stereoselective synthesis of (+)-hyptolide
Author/Authors :
Murga، نويسنده , , Juan and Garc?́a-Fortanet، نويسنده , , Jorge and Carda، نويسنده , , Miguel and Marco-Castaٌo، نويسنده , , J.Alberto، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Abstract :
The first total synthesis of the naturally occurring lactone (+)-hyptolide is described. Ethyl l-lactate was the chiral starting material. Key steps of this 15-step synthesis were a Brownʹs asymmetric allylation, a Carreiraʹs asymmetric ethynylation and a ring closing metathesis.
Keywords :
asymmetric ethynylation , (+)-hyptolide , ring-closing metathesis , Chiral pool , asymmetric allylboration
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
