Title of article
The first example of a preparative 1,4-perfluoroalkylation using (perfluoroalkyl)trimethylsilanes
Author/Authors
Sosnovskikh، نويسنده , , V.Ya and Sevenard، نويسنده , , D.V and Usachev، نويسنده , , B.I and Rِschenthaler، نويسنده , , G.-V، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
3
From page
2097
To page
2099
Abstract
Reactions of 2-perfluoroalkylchromones with (perfluoroalkyl)trimethylsilanes proceed as a 1,4-nucleophilic perfluoroalkylation to give 2,2-bis(perfluoroalkyl)chroman-4-ones in high yields after acid hydrolysis. Oxidation of 2,2-bis(trifluoromethyl)-6-methylchroman-4-one with K2S2O8 leads to fluorinated analogs of natural lactarochromal and the corresponding acid.
Keywords
2 , (perfluoroalkyl)trimethylsilanes , 2-bis(perfluoroalkyl)chroman-4-ones , trifluoromethylated analogues of natural lactarochromal and corresponding acids , 2-perfluoroalkylchromones
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1661056
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