Title of article
Activity-based fluorescent probes that target phosphatases
Author/Authors
Zhu، نويسنده , , Qing and Huang، نويسنده , , Xuan and Chen، نويسنده , , Grace Y.J and Yao، نويسنده , , Shao Q. Yao، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
2669
To page
2672
Abstract
We have successfully designed and synthesized two fluorescently-labeled, activity-based probes, Probe 1 and Probe 2, which were shown to label protein tyrosine phosphatases specifically, as well as other types of phosphatases. The probes were not reactive towards the other non-phosphatase enzymes tested. These probes may find potential applications in large-scale proteomic experiments whereby subclasses of proteins may be selectively identified.
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1661407
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