An efficient synthesis of pyrroles by a one-pot, three-component condensation of a carbonyl compound, an amine and a nitroalkene in a molten ammonium salt

A one-pot, three-component condensation of a carbonyl compound, an amine and a nitroalkene leading to an efficient synthesis of alkyl-substituted pyrroles has been carried out in molten tetrabutylammonium bromide. Neither a catalyst nor an organic solvent is required for this reaction and the molten ammonium salt is recyclable.