Title of article :
Synthesis of a potential reactivator of acetylcholinesterase—1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium)propane dibromide
Author/Authors :
Ku?a، نويسنده , , Kamil and Bielavsk?، نويسنده , , Ji??? and Cabal، نويسنده , , Ji??? and Bielavsk?، نويسنده , , Marcela، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Abstract :
Two methods for the synthesis of a new unsymmetric bispyridinium oxime-1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium)propane dibromide are described. In vitro efficacy of this new oxime to reactivate sarin-inhibited acetylcholinesterase has been evaluated.
Keywords :
Acetylcholinesterase , Oxime , reactivation , Synthesis , Sarin
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
