Author/Authors :
Serna، نويسنده , , Sonia and Tellitu، نويسنده , , Imanol and Dom??nguez، نويسنده , , Marيa Esther and Moreno Cordero، نويسنده , , Isabel and SanMartin، نويسنده , , Ra?l، نويسنده ,
Abstract :
A novel access to the isoindolinone and isoquinolin-2-one skeletons from adequately substituted aromatic precursors is described. The key intramolecular cyclization step was performed by the action of phenyliodine(III)bis(trifluoroacetate) (PIFA) on the corresponding vinyl or allyl substituted N-(p-methoxyphenyl)benzamide derivatives leading to the heterocyclic compounds through 5-exo-trig and 6-exo-trig processes, respectively.