Author/Authors :
Loussouarn، نويسنده , , Anthony and Ouadi، نويسنده , , Ali and Morandeau، نويسنده , , Laurence and Remaud، نويسنده , , Patricia and Giles، نويسنده , , Robin and Gestin، نويسنده , , Jean-Francois and Webb، نويسنده , , John، نويسنده ,
Abstract :
This study describes a simple, efficient synthesis pathway from trans-1,2-diaminocyclohexane that provides access to a new class of semi-rigid polyamine, polycarboxylic, and polyphosphonic ligands. The key steps in synthesis were the functionalisation (with an appropriate branching group) of a bisphosphonate diaminocyclohexane derivative and the introduction of methanephosphonic functions by a rarely used method.