Title of article :
Zirconium-catalyzed enantiotopic group-selective synthesis of hydrindanes
Author/Authors :
Mori، نويسنده , , Miwako and Takaki، نويسنده , , Tomoko and Makabe، نويسنده , , Muneyoshi and Sato، نويسنده , , Yoshihiro، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Abstract :
When a THF solution of 12b and (S)-(EBTHI)ZrBINOL (10 mol%) was refluxed in the presence of BuMgCl (4 equiv.) for 4 h, zirconium-catalyzed enantiotopic group-selective cyclization proceeded and hydrindane 13b with 87% ee was obtained in 35% yield.
Keywords :
zirconium-catalyzed cyclization , hydrindane , asymmetric synthesis , (EBTHI)ZrBINOL , enantiotopic group-selective synthesis , zirconacycle
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
