Title of article :
Organometallic reagent-mediated one-pot synthesis of 3,5,6-trisubstituted naphthostyrils
Author/Authors :
Liu، نويسنده , , Jin-Jun and Konzelmann، نويسنده , , Fred and Luk، نويسنده , , Kin-Chun Luk، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Abstract :
A one-pot synthesis of 3,5,6-trisubstituted naphthostyrils is described. Addition of organometallic reagents to β-iodovinyl ketone 1 followed by elimination gave the Z-form β-alkyl vinyl ketone 15. Intramolecular cyclization of 15 under the reaction conditions afforded 3,5,6-trisubstituted naphthostyrils 4.
Keywords :
trisubstituted naphthostyril , Intramolecular cyclization , C?C bond formation , organometallic reagents
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
