Title of article
The hetero-Diels–Alder addition of ethyl 2-nitrosoacrylate to electron-rich alkenes as a route to unnatural α-amino acids
Author/Authors
Gallos، نويسنده , , John K and Sarli، نويسنده , , Vassiliki C and Varvogli، نويسنده , , Anastassia C and Papadoyanni، نويسنده , , Constantina Z and Papaspyrou، نويسنده , , Sofia D and Argyropoulos، نويسنده , , Nicolaos G، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
5
From page
3905
To page
3909
Abstract
A new method for the stereoselective synthesis of nonproteinogenic α-amino acids has been developed, which involves hetero-Diels–Alder addition of ethyl 2-nitrosoacrylate to electron-rich alkenes, such as enol ethers, enamines and allylsilanes, and a further two or three step manipulation of the resulting oxazines.
Keywords
hetero-Diels–Alder addition , ethyl 2-nitrosoacrylate , Enol ethers , allylsilanes , ?-Amino acids , enamines
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1662114
Link To Document