Author/Authors :
Cuevas-Ya?ez، نويسنده , , Erick and Garc??a، نويسنده , , Mario A. and de la Mora، نويسنده , , Marco A. and Muchowski، نويسنده , , Joseph M. and Cruz-Almanza، نويسنده , , Raymundo، نويسنده ,
Abstract :
A novel, simple and mild method to prepare α-diazoketones from carboxylic acids is presented. The procedure involves the reaction of carboxylic acids with triphenylphosphine/NBS and subsequent treatment with diazomethane. 13C and 31P NMR experiments demonstrate that the process occurs through an acyloxyphosphonium salt as a key intermediate.
