Title of article
Novel synthesis of α-diazoketones from acyloxyphosphonium salts and diazomethane
Author/Authors
Cuevas-Ya?ez، نويسنده , , Erick and Garc??a، نويسنده , , Mario A. and de la Mora، نويسنده , , Marco A. and Muchowski، نويسنده , , Joseph M. and Cruz-Almanza، نويسنده , , Raymundo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
3
From page
4815
To page
4817
Abstract
A novel, simple and mild method to prepare α-diazoketones from carboxylic acids is presented. The procedure involves the reaction of carboxylic acids with triphenylphosphine/NBS and subsequent treatment with diazomethane. 13C and 31P NMR experiments demonstrate that the process occurs through an acyloxyphosphonium salt as a key intermediate.
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1662663
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