Title of article
Optimization of spiroimidazolidinone derivatives synthesis on solid phase using SynPhase™ Lanterns
Author/Authors
Bedos، نويسنده , , Philippe and Feliu، نويسنده , , Lidia and Martinez، نويسنده , , Jean and Amblard، نويسنده , , Muriel، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
3
From page
4937
To page
4939
Abstract
We report the synthesis of 1,4,8-triazaspiro[4.5]decan-2-one derivatives from N-benzyl-4-piperidone and N-protected amino acid amides on solid support. We have translated the chemistry from solution to solid phase using a backbone amide linker (BAL) mimic. Using a parallel combinatorial approach, we performed the optimization of the synthesis on SynPhase™ Lanterns.
Keywords
optimization , spiroimidazolidinone , SynPhase™ Lanterns , backbone amide linker mimic
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1662737
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