Title of article
The nickel-catalyzed Sonogashira–Hagihara reaction
Author/Authors
Beletskaya، نويسنده , , Irina P and Latyshev، نويسنده , , Gennadij V and Tsvetkov، نويسنده , , Alexey V and Lukashev، نويسنده , , Nikolai V، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
3
From page
5011
To page
5013
Abstract
The Sonogashira–Hagihara coupling of terminal acetylenes with aryl iodides in the presence of a nickel catalyst and CuI was investigated. The reaction proceeds rapidly in aqueous dioxane in the presence of Ni(PPh3)2Cl2 with high yields of disubstituted tolanes being obtained. The reaction seems to be an inexpensive alternative to the palladium-catalyzed process.
Keywords
Sonogashira–Hagihara coupling , Nickel catalyst , tolanes
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1662781
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