Title of article
Novel strategic lipase-catalyzed asymmetrization of 1,3-propanediacetate in supercritical carbon dioxide
Author/Authors
Mase، نويسنده , , Nobuyuki and Sako، نويسنده , , Takeshi and Horikawa، نويسنده , , Yoshiteru and Takabe، نويسنده , , Kunihiko، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
5175
To page
5178
Abstract
In lipase-catalyzed asymmetrization of 1,3-propanediacetate no enantioselectivity was observed in conventional organic solvents, whereas in supercritical carbon dioxide (scCO2) enantioselectivities were observed up to 50% ee, which probably arose from a conformational changing of lipase at the active site due to a transformation of the amino group of lysine into carbamic acid.
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1662880
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