• Title of article

    Syntheses of new water-soluble dicobalt complexes having two cobaltcarbon bonds and their ability for DNA cleavage

  • Author/Authors

    Shimakoshi، نويسنده , , Hisashi and Kaieda، نويسنده , , Takeshi and Matsuo، نويسنده , , Takashi and Sato، نويسنده , , Hideaki and Hisaeda، نويسنده , , Yoshio، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2003
  • Pages
    3
  • From page
    5197
  • To page
    5199
  • Abstract
    One-pot syntheses of new water-soluble dicobalt complexes having two cobaltcarbon bonds are reported. The complexes were characterized by 1H NMR and UV–vis spectroscopies as well as ESI-MS. These complexes were photosensitive, and photo-cleavage of the cobaltcarbon bonds upon irradiation with visible light produced methyl radicals which were detected by ESR spin-trapping techniques. The dicobalt complexes exhibited high ability for DNA cleavage in comparison with that for the corresponding monocobalt complex.
  • Keywords
    DNA cleavage , cobalt?carbon bond , dicobalt complex , Water-Soluble
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2003
  • Journal title
    Tetrahedron Letters
  • Record number

    1662897

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1662897