Title of article
Diene(tricarbonyl)iron complexes linked to spirooxazolones for the synthesis of cyclopropyldihydroxyphenylalanine
Author/Authors
Schumacher، نويسنده , , Marc and Miesch، نويسنده , , Laurence and Franck-Neumann، نويسنده , , Michel، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
3
From page
5393
To page
5395
Abstract
Complexed cyclopropyl-3,4-dihydroxyphenylalanine (∇ DOPA) were synthesized by diazomethane cyclopropanation of the appropriate diene(tricarbonyl)iron complexes linked to azlactones. Opening of the oxazolone ring by treatment with MeOH and DMAP gave the corresponding methyl esters. Introduction of the Boc group, cleavage of the carbamate with hydrazine provided Boc-protected cyclopropylogs of dl-dihydroxyphenylalanine.
Keywords
hydrazine , Diazomethane , spiroazlactones , oxazolones , diene(tricarbonyl)iron complexes , cyclopropyldihydroxyphenylalanine
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1663017
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