Calibration of potentiometric sensor arrays with a reduced number of standards

In this paper a novel calibration procedure for the parameter determination of ion-selective electrodes used in an array is described. Commonly used procedures require a large number of standards to determine the parameters based on the Nicolsky–Eisenman model. The elaborated procedure reduces the number of standards to a minimum by using a standard containing a mixture of ions instead of a couple of pure standards. This paper presents a complete calibration procedure, which consists of designing the composition of the standards, parameter determination and verification of the calibration results. Comparison of the results obtained by the procedure presented with results obtained by the Two-Point Calibration and Separate Solution methods proves that the accuracies of both procedures are comparable. The outlined procedure can be applied in multicomponent analysers.