Theory and computer simulation of the time-dependent selectivity behavior of polymeric membrane ion-selective electrodes

A theoretical treatment of the time-dependent potential response of ion-selective electrodes to sample solutions containing primary and interfering ions is presented. The theory accounts for the influence of ion fluxes in the electrode membrane and the contacting aqueous sample layer and describes the variations in the apparent selectivity behavior as a function of the measuring time. The applicability of the theory is demonstrated by comparing predicted response curves with results of virtual experiments based on computer simulation. A close and convincing agreement was achieved for a large series of different examples, which confirms that the new theory can be successfully applied for general cases.