Title of article
Development of a high-performance liquid chromatographic method for the determination of 11-keto-β-boswellic acid in human plasma
Author/Authors
Tawab، نويسنده , , Mona Abdel and Kaunzinger، نويسنده , , Astrid and Bahr، نويسنده , , Ute and Karas، نويسنده , , Michael and Wurglics، نويسنده , , Mario and Schubert-Zsilavecz، نويسنده , , Manfred، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
7
From page
221
To page
227
Abstract
A validated HPLC method for the determination of 11-keto-β-boswellic acid (KBA) in human plasma was developed. The method involves the solid-phase extraction of KBA from plasma followed by a separation with reversed-phase HPLC. Calibration was based on external standardisation and ranged between 0.1 and 2.0 μg KBA per ml plasma. Linearity was established over the entire calibration range and in each case the coefficient of correlation (r2) was above 0.99. The recovery of KBA from plasma was 85.7%. It was further demonstrated that the method can be applied successfully to monitor the level of KBA in plasma.
Keywords
11-Keto-?-boswellic acid
Journal title
Journal of Chromatography B Biomedical Sciences and Applications
Serial Year
2001
Journal title
Journal of Chromatography B Biomedical Sciences and Applications
Record number
1705747
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