Enantioselective hydrolyses of α-methylated cyclohexyl acetates by the cultured cells of Marchantia polymorpha

A high enantioselectivity was observed in the hydrolyses of racemic α-methylated cyclohexyl acetates with the cultured cells of Marchantia polymorpha. The enantiomeric excesses of alcohols obtained in the hydrolyses were correlated with the torsional angles between the acetoxyl and α-methyl groups. They have made it possible to predict the optical purity as well as the absolute stereochemistry of alcohols hydrolyzed by using the cultured cells of M. polymorpha.