Author/Authors :
Mart??nkov?، نويسنده , , Ludmila and Klempier، نويسنده , , Norbert and Bardakji، نويسنده , , Joseph and Kandelbauer، نويسنده , , Andreas and Ovesn?، نويسنده , , M?ria and Poda?ilov?، نويسنده , , Tereza and Kuzma، نويسنده , , Marek and P?epechalov?، نويسنده , , Irena and Griengl، نويسنده , , Herfried and Kren، نويسنده , , Vladim??r، نويسنده ,
Abstract :
Whole cells of Rhodococcus equi A4 chemoselectively hydrolyzed methyl (R,S)-3-benzoyloxy-4-cyanobutanoate and methyl (R,S)-3-benzyloxy-4-cyanobutanoate into monomethyl (R,S)-3-benzoyloxyglutarate and monomethyl (R,S)-3-benzyloxyglutarate, respectively. The intermediates of the biotransformations were the corresponding amides which were also obtained using the purified nitrile hydratase from the same microorganism.
Keywords :
Monomethyl glutarates , Rhodococcus equi , Nitrile hydratase , Cyanobutanoates , amidase
