Title of article
Biotransformation of 3-substituted methyl (R,S)-4-cyanobutanoates with nitrile- and amide-converting biocatalysts
Author/Authors
Mart??nkov?، نويسنده , , Ludmila and Klempier، نويسنده , , Norbert and Bardakji، نويسنده , , Joseph and Kandelbauer، نويسنده , , Andreas and Ovesn?، نويسنده , , M?ria and Poda?ilov?، نويسنده , , Tereza and Kuzma، نويسنده , , Marek and P?epechalov?، نويسنده , , Irena and Griengl، نويسنده , , Herfried and Kren، نويسنده , , Vladim??r، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
5
From page
95
To page
99
Abstract
Whole cells of Rhodococcus equi A4 chemoselectively hydrolyzed methyl (R,S)-3-benzoyloxy-4-cyanobutanoate and methyl (R,S)-3-benzyloxy-4-cyanobutanoate into monomethyl (R,S)-3-benzoyloxyglutarate and monomethyl (R,S)-3-benzyloxyglutarate, respectively. The intermediates of the biotransformations were the corresponding amides which were also obtained using the purified nitrile hydratase from the same microorganism.
Keywords
Monomethyl glutarates , Rhodococcus equi , Nitrile hydratase , Cyanobutanoates , amidase
Journal title
Journal of Molecular Catalysis B Enzymatic
Serial Year
2001
Journal title
Journal of Molecular Catalysis B Enzymatic
Record number
1709091
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