Title of article
Biocatalytic asymmetric hydrolysis of (±)-β-hydroxy nitriles by Rhodococcus sp. CGMCC 0497
Author/Authors
Wu، نويسنده , , Zhong-Liu and Li، نويسنده , , Zu-Yi، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
8
From page
105
To page
112
Abstract
The asymmetric hydrolysis of several 3-hydroxy-4-aryloxybutanenitriles using Rhodococcus sp. CGMCC 0497 was studied. It was revealed that the reaction temperature of 20 °C was more effective than that conventional incubation temperature such as 30 °C. The products, (R)-amides and (S)-acids, were obtained in enantiomeric excesses of up to 87%.
Keywords
?-Hydroxy nitriles , Rhodococcus , Nitrile hydratase , amidase , kinetic resolution
Journal title
Journal of Molecular Catalysis B Enzymatic
Serial Year
2003
Journal title
Journal of Molecular Catalysis B Enzymatic
Record number
1709659
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