Future direction of molecular display by yeast-cell surface engineering

Cell surface engineering using yeast cells has developed in many fields of biotechnology. Active peptides and proteins with larger size of molecules can be displayed on the yeast-cell surface than with the phage display system, although the latter has greater transformation efficiency. Because of these aspects, the yeast-cell surface engineering system represents a novel field of protein-engineering and protein creation. In this review, its future directions are described and discussed.