Title of article
Bioreduction of 2-azido-1-arylethanones mediated by Geotrichum candidum and Rhodotorula glutinis
Author/Authors
Fardelone، نويسنده , , Lucيdio C. and Rodrigues، نويسنده , , J. Augusto R. and Moran، نويسنده , , Paulo J.S.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
4
From page
9
To page
12
Abstract
Enantioselective reductions of p-X-C6H4C(O)CH2N3 (X = H, Cl, Br, CH3, OCH3) mediated by Rhodotorula glutinis and Geotrichum candidum afforded the corresponding alcohols with complementary R and S configurations, respectively, in excellent yield and enantiomeric excesses. The obtained (R)-azidoalcohols are important starting materials for preparation of natural products and valuable pharmaceutical compounds such as (R)-Tembamide and (R)-Aegeline.
Keywords
(R)- and (S)-2-azido-1-arylethanol , Tembamide , Aegeline
Journal title
Journal of Molecular Catalysis B Enzymatic
Serial Year
2006
Journal title
Journal of Molecular Catalysis B Enzymatic
Record number
1710788
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