Title of article :
Microbial transformation of 10-deacetylbaccatin III (10-DAB) by Curvularia lunata and Trametes hirsuta
Author/Authors :
Arnone، نويسنده , , Alberto and Bava، نويسنده , , Adriana and Alemani، نويسنده , , Stefano and Nasini، نويسنده , , Gianluca and Bombardelli، نويسنده , , Ezio and Fontana، نويسنده , , Gabriele، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
The microbial transformation of 10-deacetylbaccatin III (10-DAB) (1a) and 13-DeBAC (4b) was investigated. Trametes hirsuta induced 13-oxidation of 10-DAB to give (4a) in high yield, whereas incubation with Curvularia lunata resulted in the isolation of the 7-epi-10-DAB (2) and the 7-epi-10-oxo-10-DAB (3). 13-DeBAC (4b) was biotransformed into compounds (4a) and (4c) by Alternaria alternata.
Keywords :
Taxanes , 10-DAB , 13-DeBAC , Biotransformations , fungi
Journal title :
Journal of Molecular Catalysis B Enzymatic
Journal title :
Journal of Molecular Catalysis B Enzymatic
