Author/Authors :
Kawasaki، نويسنده , , Masashi and Asano، نويسنده , , Yuka and Katayama، نويسنده , , Kanako and Inoue، نويسنده , , Akihisa and Hiraoka، نويسنده , , Chiho and Kakuda، نويسنده , , Hiroko and Tanaka، نويسنده , , Akira and Goto، نويسنده , , Michimasa and Toyooka، نويسنده , , Naoki and Kometani، نويسنده , , Tadashi، نويسنده ,
Abstract :
2-Substituted 4-chromanones were synthesized in their optically active forms. The chiral intermediates were obtained via lipase-catalyzed enantioselective reactions. Lipase and esterase were also used for the hydrolysis of ester moieties of the precursors of the target compounds under mild conditions.
Keywords :
asymmetric synthesis , Hydrolysis , RESOLUTION , Chromanones , Enzyme
