Utility of ionic liquid for improvement of fluorination reaction with immobilized fluorinase

The utility of immobilized fluorinase derived from fluorinase, KF, SAM and water-absorbing polymer for the improvement of biological fluorination, giving 5′-fluoro-5′-deoxyadenosine from S-adenosyl-L-methionine, was described. Further, the contribution of ionic liquids in the fluorination reaction with immobilized fluorinase was mentioned.