Author/Authors :
Paravidino، نويسنده , , Monica and Holt، نويسنده , , Jarle and Romano، نويسنده , , Diego and Singh، نويسنده , , Neetu and Arends، نويسنده , , Isabel W.C.E. and Minnaard، نويسنده , , Adriaan J. and Orru، نويسنده , , Romano V.A. and Molinari، نويسنده , , Francesco and Hanefeld، نويسنده , , Ulf، نويسنده ,
Abstract :
Mycelia containing carboxyl-esterases, a novel source of enzymes, have been investigated in the hydrolytic kinetic resolution of one type of tert-alcohols, α,α-disubstituted cyanohydrins. This class of enzymes was found to be both active and selective towards these tert-alcohols, giving E-values as high as 42.
Keywords :
cyanohydrins , mycelium , Hydrolases , tert-Alcohols , enzyme catalysis