Title of article :
Regioselective alcoholysis of silybin A and B acetates with lipases
Author/Authors :
Purchartov?، نويسنده , , Kate?ina and Marhol، نويسنده , , Petr and Ga??k، نويسنده , , Radek and Monti، نويسنده , , Daniela and Riva، نويسنده , , Sergio and Kuzma، نويسنده , , Marek and K?en، نويسنده , , Vladim?r، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2011
Abstract :
Large screening identified lipase AK to be capable of the selective deacetylation of pentaacetyl silybins A and B to yield 3,5,20,23-tetra-O-acetyl-silybins A and B, and 3,20,23-tri-O-acetyl-silybins A and B, respectively. Deacetylation occurred at phenolic OH groups, only. These new compounds prepared from the optically pure silybins can serve as new stereochemically pure synthons for selective silybin modifications.
Keywords :
Silymarin , Silibinin , Lipase , Silybin B , deacylation
Journal title :
Journal of Molecular Catalysis B Enzymatic
Journal title :
Journal of Molecular Catalysis B Enzymatic
