Title of article
Baker’s yeast mediated preparation of (10-alkyl-10H-phenothiazin-3-yl)methanols
Author/Authors
To?a، نويسنده , , Monica and Paizs، نويسنده , , Csaba and Majdik، نويسنده , , Cornelia and Moldovan، نويسنده , , Paula and Nov?k، نويسنده , , Lajos and Kolonits، نويسنده , , P?l and Szab?، نويسنده , , Eva and Poppe، نويسنده , , L?szl? and Irimie، نويسنده , , Florin-Dan Irimie، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
8
From page
241
To page
248
Abstract
A series of 10-alkyl-10H-phenothiazine-3-carbaldehydes (2a–h) were obtained by Vilsmeier–Haack formylation from the corresponding 10-alkyl-10H-phenothiazines (1a–h) and reduced to (10-alkyl-10H-phenothiazine-3-yl)methanols (3a–h) by two alternative methods. The baker’s yeast catalyzed reaction proved to be superior over the NaBH4 reduction and yielded the desired 3-hydroxymethylphenothiazines (3a–h) almost quantitatively.
Keywords
N-alkylphenothiazines , Aldehydes , Formylation , Baker’s yeast , Reduction
Journal title
Journal of Molecular Catalysis B Enzymatic
Serial Year
2002
Journal title
Journal of Molecular Catalysis B Enzymatic
Record number
1715976
Link To Document