• Title of article

    Modeling mutant distribution in a stressed Escherichia coli bacteria population using experimental data

  • Author/Authors

    Bazzani، نويسنده , , Armando and Fani، نويسنده , , Renato and Freguglia، نويسنده , , Paolo، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2014
  • Pages
    7
  • From page
    320
  • To page
    326
  • Abstract
    In this paper we propose a statistical physics approach to experimental results on bacterial mutations (Escherichia coli). We get scaling laws that describe some generic traits and suggest some features of the underlying dynamical structure for the considered evolution process. Our main assumption is that the evolution dynamics could be visualized as a random walk on a fitness landscape whose topological structure is analogous to the structure of energy landscape potentials used in Physics and Chemistry. Then we relate the generic distribution of local minima attraction basins to the number of bacterial mutations and we discuss the comparison with experimental results.
  • Keywords
    random processes , Bacterial mutation , Fitness landscape , Scaling laws
  • Journal title
    Physica A Statistical Mechanics and its Applications
  • Serial Year
    2014
  • Journal title
    Physica A Statistical Mechanics and its Applications
  • Record number

    1737692