Transport processes and irreversible thermodynamics analysis in tumoral systems

Cells are chemical engines in which specific ordered chemical reactions occur. Cancer can be described as an open complex dynamic and self-organizing system. Entropy generation approach has been used to evaluate the biochemical and biophysical conditions of the stationary states for tumoral cells, in relation to the transport processes through their membrane. The tumoral systems can assume all the values of volume, temperature, chemical reaction rate and the time of chemical reaction, in the range of stationary conditions. This range can be evaluated by the principle of extrema variation of the entropy generation. Outside this range, cancer cannot develop and dies. The geometrical characteristics are fundamental in the growth of cancer. The fractal dimensions are discussed in this analysis and the geometry of cancer is related to the entropy generation. A possible anticancer thermodynamic approach has been suggested.