Author/Authors :
Monte، نويسنده , , Leonardo G. and Jorge، نويسنده , , Sérgio and Xavier، نويسنده , , Marina A. and Leal، نويسنده , , Fernanda M.A. and Amaral، نويسنده , , Marta G. and Seixas، نويسنده , , Fabiana K. and Dellagostin، نويسنده , , Odir A. and Hartleben، نويسنده , , Clلudia P.، نويسنده ,
Abstract :
Leptospirosis is a worldwide zoonotic infection caused by pathogenic Leptospira. Synanthropic rodents are recognized carriers of leptospires; however, the role of wild rodents in the epidemiology of the disease is still incipient. In this work, we describe Leptospira strain isolated from Cavia aperea (Brazilian guinea pig). The isolated strain was characterized by partial rpoB gene sequencing, variable-number tandem-repeats and histopathological analysis. The strain was identified as Leptospira interrogans, serogroup Icterohaemorrhagiae and caused clinical signs of leptospirosis in the hamster model, attesting to its virulence. In conclusion, these findings could be useful for elucidating the epidemiological role of C. aperea in leptospirosis.
