Title of article :
Porous NiTi for bone implants: A review
Author/Authors :
Bansiddhi، نويسنده , , A. and Sargeant، نويسنده , , T.D. and Stupp، نويسنده , , S.I. and Dunand، نويسنده , , D.C.، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2008
Pages :
10
From page :
773
To page :
782
Abstract :
NiTi foams are unique among biocompatible porous metals because of their high recovery strain (due to the shape-memory or superelastic effects) and their low stiffness facilitating integration with bone structures. To optimize NiTi foams for bone implant applications, two key areas are under active study: synthesis of foams with optimal architectures, microstructure and mechanical properties; and tailoring of biological interactions through modifications of pore surfaces. This article reviews recent research on NiTi foams for bone replacement, focusing on three specific topics: (i) surface modifications designed to create bio-inert porous NiTi surfaces with low Ni release and corrosion, as well as bioactive surfaces to enhance and accelerate biological activity; (ii) in vitro and in vivo biocompatibility studies to confirm the long-term safety of porous NiTi implants; and (iii) biological evaluations for specific applications, such as in intervertebral fusion devices and bone tissue scaffolds. Possible future directions for bio-performance and processing studies are discussed that could lead to optimized porous NiTi implants.
Keywords :
Cellular metals , Nitinol , Chemical modification , Bioactive surfaces , Biocompatibility
Journal title :
Acta Biomaterialia
Serial Year :
2008
Journal title :
Acta Biomaterialia
Record number :
1752490
Link To Document :
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