Title of article :
Future Directions for Cardiovascular Disease Comparative Effectiveness Research: Report of a Workshop Sponsored by the National Heart, Lung, and Blood Institute
Author/Authors :
Hlatky، نويسنده , , Mark A. and Douglas، نويسنده , , Pamela S. and Cook، نويسنده , , Nakela L. and Wells، نويسنده , , Barbara and Benjamin، نويسنده , , Emelia J. and Dickersin، نويسنده , , Kay and Goff، نويسنده , , David C. and Hirsch، نويسنده , , Alan T. and Hylek، نويسنده , , Elaine M. and Peterson، نويسنده , , Eric D. and Roger، نويسنده , , Véronique L. and Selby، نويسنده , , Joseph V. and Udelson، نويسنده , , James E. and Lauer، نويسنده , , Michael S.، نويسنده ,
Abstract :
Comparative effectiveness research (CER) aims to provide decision makers with the evidence needed to evaluate the benefits and harms of alternative clinical management strategies. CER has become a national priority, with considerable new research funding allocated. Cardiovascular disease is a priority area for CER. This workshop report provides an overview of CER methods, with an emphasis on practical clinical trials and observational treatment comparisons. The report also details recommendations to the National Heart, Lung, and Blood Institute for a new framework for evidence development to foster cardiovascular CER, and specific studies to address 8 clinical issues identified by the Institute of Medicine as high priorities for cardiovascular CER.