Author/Authors :
Sadeghi، Bahareh نويسنده Hematology Department, Faculty of Medical Science, Tarbiat Modarres University, Tehran, Iran , , Ghorbani Rad، Maryam نويسنده Department of Chemistry, Yazd Branch, Islamic Azad University, P.O. Box 89195-155, Yazd, Iran ,
Abstract :
Reaction between aromatic aldehydes and 3–methyl-1-phenyl-2-pyrazoline-5-one catalyzed by nano-SiO2/HClO4 in water under reflux provided a simple and efficient route for the synthesis of 4-((5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)(aryl)methyl)-3-methyl-1-phenyl-1H-pyrazol-5-ol derivatives in high yields.