Author/Authors :
Hart، نويسنده , , Alister J. and Quinn، نويسنده , , Paul D. and Lali، نويسنده , , Ferdinand and Sampson، نويسنده , , Barry and Skinner، نويسنده , , John A. and Powell، نويسنده , , Jonathan J. and Nolan، نويسنده , , John and Tucker، نويسنده , , Keith and Donell، نويسنده , , Simon and Flanagan، نويسنده , , Adrienne and Mosselmans، نويسنده , , J. Fred W. Mosselmans، نويسنده ,
Abstract :
Some types of metal-on-metal (MOM) hip replacements have unacceptably high rates of failure, such as the Ultima TPS MOM hip, with 13.8% failure at 5 years. This has been attributed to an inflammatory reaction following the release of cobalt (Co) and chromium (Cr) from the bearing surfaces and modular junctions. There is in vitro evidence that Co is more important than Cr in the inflammatory process, but there are no reported human tissue studies of the analysis of implant-derived metals.
Keywords :
Synchrotron , Metal-on-metal hip arthroplasty , CHEMICAL ANALYSIS , Periprosthetic tissue , Inflammatory response
