Title of article
Dendrimer–drug interactions
Author/Authors
DʹEmanuele، نويسنده , , Antony and Attwood، نويسنده , , David، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
16
From page
2147
To page
2162
Abstract
The interaction between drugs and dendrimers is reviewed with particular reference to the entrapment of drugs within the dendrimer architecture and the electrostatic and covalent complexation of drugs to the dendrimer surface. The application of dendrimer–drug complexation in the enhancement of drug solubility and bioavailability and the use of the complexes as vehicles for the controlled release of drugs and drug targeting is discussed.
Keywords
Conjugation , PEGylation , block copolymers , Encapsulation , Solubility enhancement , Dendrimers , Electrostatic Interaction
Journal title
Advanced Drug Delivery Reviews
Serial Year
2005
Journal title
Advanced Drug Delivery Reviews
Record number
1761664
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