Hemorheological and cardiovascular effects of exercise training in the rehabilitation of elderly patients with chronic obstructive pulmonary disease

The purpose of this study is to evaluate hemorheological effects of a single exercise respiratory session (SERS), in the rehabilitation of elderly patients with chronic obstructive pulmonary disease (COPD). Fifteen elderly patients with COPD and 15 controls, matched for demographic variables and body habitus, were submitted to a single session of relaxation and unsupported upper-extremity exercise, coordinated with breathing. We measured hemogasanalytical and cardiovascular parameters: hematocrit value, platelet aggregation, β-TG and PF4 plasma levels, blood viscosity and erythrocyte filterability. In both groups, SERS significantly decreased platelet aggregation (P<0.05), β-TG and PF4 plasma levels (P<0.05). Erythrocyte filterability and diastolic blood pressure showed a trend to increase in both groups but reached a significant difference in patients with COPD only. Respiratory exercise has a positive influence on platelet and hemorheological parameters in the elderly with COPD. The increase of diastolic blood pressure requires active surveillance.